KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
MED1
All Species:
23.64
Human Site:
Y1132
Identified Species:
47.27
UniProt:
Q15648
Number Species:
11
Phosphosite Substitution
Charge Score:
0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q15648
NP_004765.2
1581
168478
Y1132
S
K
L
S
S
S
M
Y
S
S
Q
G
S
S
G
Chimpanzee
Pan troglodytes
XP_001172395
1581
168474
Y1132
S
K
L
S
S
S
M
Y
S
S
Q
G
S
S
G
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_537654
1583
168625
Y1134
S
K
L
S
S
S
V
Y
S
S
Q
G
S
S
G
Cat
Felis silvestris
Mouse
Mus musculus
Q925J9
1575
167122
Y1134
S
K
L
S
G
S
M
Y
A
S
Q
G
S
S
G
Rat
Rattus norvegicus
NP_001127833
1567
166392
Y1118
A
K
L
S
G
S
M
Y
S
S
Q
G
S
S
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001521297
422
46589
Chicken
Gallus gallus
XP_418125
1594
169410
Y1143
S
K
M
S
S
S
L
Y
S
S
Q
G
G
S
S
Frog
Xenopus laevis
Q6INP8
1570
165663
Q1123
G
G
G
M
Y
S
G
Q
S
G
Q
S
S
S
Q
Zebra Danio
Brachydanio rerio
XP_700209
1694
176982
Q1190
K
L
E
S
S
V
G
Q
G
N
I
A
K
Q
S
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9VP05
1475
149513
G1055
V
G
A
G
A
G
A
G
A
G
A
S
G
L
E
Honey Bee
Apis mellifera
XP_395879
1811
193227
D1358
F
P
S
K
G
I
G
D
R
K
S
S
P
S
G
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_786427
2421
258175
S1578
T
S
S
T
S
S
S
S
S
V
R
S
V
S
V
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.9
N.A.
98
N.A.
94.4
93.9
N.A.
24.4
87.6
72.5
56.4
N.A.
22
24.4
N.A.
25.7
Protein Similarity:
100
100
N.A.
98.9
N.A.
97.1
96.5
N.A.
25.7
93.5
81.7
69
N.A.
38.9
41.1
N.A.
38.5
P-Site Identity:
100
100
N.A.
93.3
N.A.
86.6
86.6
N.A.
0
73.3
33.3
13.3
N.A.
0
13.3
N.A.
26.6
P-Site Similarity:
100
100
N.A.
100
N.A.
93.3
93.3
N.A.
0
86.6
33.3
20
N.A.
13.3
13.3
N.A.
46.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
9
0
9
0
9
0
9
0
17
0
9
9
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
9
0
0
0
0
0
0
0
% D
% Glu:
0
0
9
0
0
0
0
0
0
0
0
0
0
0
9
% E
% Phe:
9
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
9
17
9
9
25
9
25
9
9
17
0
50
17
0
50
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
0
0
0
0
9
0
0
0
0
9
0
0
0
0
% I
% Lys:
9
50
0
9
0
0
0
0
0
9
0
0
9
0
0
% K
% Leu:
0
9
42
0
0
0
9
0
0
0
0
0
0
9
0
% L
% Met:
0
0
9
9
0
0
34
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
0
0
9
0
0
0
0
0
% N
% Pro:
0
9
0
0
0
0
0
0
0
0
0
0
9
0
0
% P
% Gln:
0
0
0
0
0
0
0
17
0
0
59
0
0
9
9
% Q
% Arg:
0
0
0
0
0
0
0
0
9
0
9
0
0
0
0
% R
% Ser:
42
9
17
59
50
67
9
9
59
50
9
34
50
75
17
% S
% Thr:
9
0
0
9
0
0
0
0
0
0
0
0
0
0
0
% T
% Val:
9
0
0
0
0
9
9
0
0
9
0
0
9
0
9
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
9
0
0
50
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _